Publications using the BOTL microarray platform

• Comparison of gene expression by co-cultured WC1+ gammadelta and CD4+ alphabeta T cells exhibiting a recall response to bacterial antigen. Blumerman SL; Herzig CT; Wang F; Coussens PM; and Baldwin CL. Mol Immunol. 2007 Mar;44(8):2023-35.
  
  
• Gene expression profiling of peripheral blood mononuclear cells (PBMC) from Mycobacterium bovis infected cattle after in vitro antigenic stimulation with purified protein derivative of tuberculin (PPD). Meade KG; Gormley E; Park SDE; Fitzsimons T; Rosa GJM; Costello E; Keane J; Coussens PM; and MacHugh DE. Veterinary Immunology and Immunopathology 2006 Sept 15;113(1-2):73-89
  
  
• Molecular Evidence That Growth of Dominant Follicles Involves a Reduction in Follicle-Stimulating Hormone Dependence and an Increase in Luteinizing Hormone Dependence in Cattle. Mihm M; Baker PJ; Ireland JLH; Smith GW; Coussens PM; Evans ACO; and Ireland JJ. Biology of Reproduction. 2006;74:1051-1059
  
  
• Suppressed expression of genes involved in transcription and translation in in-vitro compared with in-vivo cultured bovine embryos. Corcoran D; Fair T; Park S; Rizos D; Patel OV; Smith GW; Coussens PM; Ireland JJ; Boland MP; Evans AC; Lonergan P. Reproduction, April 2006, 131 (4): 651-660.
  
  
• Differential expression of genes encoding CD30L and P-selectin in cattle with Johne's disease: Progress toward a diagnostic gene expression signature. Skovgaard K; Grell SN; Heegaard PMH; Jungersen G; Pudrith CB; Coussens PM. Veterinary Immunology and Immunopathology 2006 Aug 15;112(3-4):210-224
  
  
• Understanding bovine trypanosomiasis and trypanotolerance: the promise of functional genomics. Hill EW; O"Gorman GM; Agaba M; Gibson JP; Hanotte O; Kemp SJ; Naessens J; Coussens PM; MacHugh DE. Veterinary Immunology and Immunopathology 2005 May 15;105(3-4):247-258
  
  
• Gene expression profile of mechanically impacted bovine articular cartilage explants. Chan PS; Schlueter AE; Coussens PM; Rosa GJM; Haut RC; Orth MW. Journal of Orthopaedic Research, Sep 2005. 23(5): 1146-1151.
  
  
• Gene expression signatures in neutrophils exposed to glucocorticoids: a new paradigm to help explain "neutrophil dysfunction" in parturient dairy cows. Burton JL; Madsen SA; Chang LC; Weber PS; Buckham KR; van Dorp R; Hickey MC; Earley B.Veterinary Immunology and Immunopathology 2005 May 15;105(3-4):197-219.
  
  
• Johne's disease in cattle is associated with enhanced expression of genes encoding IL-5, GATA-3, tissue inhibitors of matrix metalloproteinases 1 and 2, and factors promoting apoptosis in peripheral blood mononuclear cells. Coussens PM; Pudrith CB; Skovgaard K; Ren XN; Suchyta SP; Stabel JR; Heegaard PMH.Veterinary Immunology and Immunopathology 2005 May 15;105(3-4):221-234
  
  
• Immunorelevant gene expression in LPS-challenged bovine mammary epithelial cells. Pareek R; Wellnitz O; VanDorp R; Burton J; Kerr D. Journal of Applied Genetics 2005;46(2):171-177.
  
  
• Rapid and transient activation of gene expression in peripheral blood mononuclear cells from Johne's disease positive cows exposed to Mycobacterium paratuberculosis in vitro. Coussens PM; Jeffers A; Colvin C. Microbial Pathogenesis 2004 Feb;36(2):93-108.
  
  
• Microarray analysis of gene expression in blood neutrophils of parturient cows. Madsen SA; Chang LC; Hickey MC; Rosa GJ; Coussens PM; Burton JL. Physiological Genomics. 2004 Jan 15;16(2):212-21.
  
  
• Enhanced expression of interleukin-1alpha and tumor necrosis factor receptor-associated protein 1 in ileal tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis. Aho AD; McNulty AM; Coussens PM. Infection and Immunity 2003 Nov;71(11):6479-86.
  
  
• Evidence for a novel gene expression program in peripheral blood mononuclear cells from Mycobacterium avium subsp. paratuberculosis-infected cattle. Coussens PM; Colvin CF; Rosa GJ; Perez-Laspiur J; Elftman MD. Infection and Immunity 2003 Nov;71(11):6487-98.
  
  
• Gene expression profiling of peripheral blood mononuclear cells from cattle infected with Mycobacterium paratuberculosis. Coussens PM; Colvin CJ; Wiersma K; Abouzied A; Sipkovsky S. Infection and Immunity 2002 Oct;70(10):5494-502.
  
  
• Bioinformatics and high throughput approach to create genomic resources for the study of bovine immunobiology. Coussens PM; Nobis W. Veterinary Immunology and Immunopathology 2002 Jul;86(3-4):229-44.
  
  
• Generation of EST and cDNA microarray resources for the study of bovine immunobiology. Yao J; Burton JL; Saama P; Sipkovsky S; Coussens PM. Acta Veterinaria Scandinavica 2001;42(3):391-405.
  
  
• An immunogenomics approach to understanding periparturient immunosuppression and mastitis susceptibility in dairy cows. Burton JL; Madsen SA; Yao J; Sipkovsky SS; Coussens PM. Acta Veterinaria Scandinavica 2001;42(3):407-24.